What is clinical trial?

  • (noun): A rigorously controlled test of a new drug or a new invasive medical device on human subjects; in the United States it is conducted under the direction of the FDA before being made available for general clinical use.
    Synonyms: clinical test

Clinical Trial

Clinical trials are sets of tests in medical research and drug development that generate safety and efficacy data (or more specifically, information about adverse drug reactions and adverse effects of other treatments) for health interventions (e.g., drugs, diagnostics, devices, therapy protocols). They're conducted only after satisfactory information has been gathered on the quality of the nonclinical safety, and health authority/ethics committee approval is granted in the country where approval of the drug or device is sought.

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Some articles on clinical trial:

Cancer Vax - Products - Canvaxin
3, 2005, CancerVax announced the discontinuation of its Phase 3 clinical trial of Canvaxin in patients with Stage III melanoma ... with oversight responsibility for the clinical trial ... at the third interim analysis, that it was unlikely that the trial would provide significant evidence of a survival benefit for Canvaxin-treated patients versus those receiving placebo ...
Clinical Trial - Controversy
... editorial, published in each journal, on the control over clinical trials exerted by sponsors, particularly targeting the use of contracts which allow sponsors to review ... Researchers may be restricted from contributing to the trial design, accessing the raw data, and interpreting the results ... Seeding trials are particularly controversial ...
Latrepirdine - Uses - Alzheimer's Disease: Failed Clinical Trial
2009 after being shown in small preclinical trials to have positive effects on persons suffering from Alzheimer’s disease ... Preliminary results from human trials have also been promising ... In an initial six-month phase II trial, results have shown significant improvement over placebo at 12 months ...
Case Report Form
... report form (or CRF) is a paper or electronic questionnaire specifically used in clinical trial research ... The Case Report Form is the tool used by the sponsor of the clinical trial to collect data from each participating site ... All data on each patient participating in a clinical trial are held and/or documented in the CRF, including adverse events ...

Famous quotes containing the word trial:

    A trial cannot be conducted by announcing the general culpability of a civilization. Only the actual deeds which, at least, stank in the nostrils of the entire world were brought to judgment.
    Albert Camus (1913–1960)