What are okazaki fragments?

Okazaki Fragments

Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication. They are complementary to the lagging template strand, together forming short double-stranded DNA sections. Okazaki fragments are between 1,000 to 2,000 nucleotides long in Escherichia coli and are between 100 to 200 nucleotides long in eukaryotes. They are separated by ~10-nucleotide RNA primers and are unligated until RNA primers are removed, followed by enzyme ligase connecting (ligating) the two Okazaki fragments into one continuous newly synthesized complementary strand.

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Uses in Technology - Engineering Concepts Associated With Okazaki Fragments
... Due to the importance and purpose of Okazaki fragments in DNA replication, bioengineers are using these pieces of DNA in their research ... using DNA base exploration and information about Okazaki fragment synthesis ... Based on the relative position of Okazaki fragments to the replication fork during lagging stand synthesis as well as the average length of Okazaki fragments during replication, the scientists were ...

Famous quotes containing the word fragments:

    These fragments I have shored against my ruins.
    —T.S. (Thomas Stearns)