Role in Disease or Disorder
Diseases of the ventricular system include abnormal enlargement (hydrocephalus) and inflammation of the CSF spaces (meningitis, ventriculitis) caused by infection or introduction of blood following trauma or hemorrhage.
Interestingly, scientific study of CT scans of the ventricles in the late 1970s revolutionized the study of mental disorder. Researchers found that individuals with schizophrenia had (in terms of group averages) enlarged ventricles compared to healthy subjects. This became the first "evidence" that schizophrenia was biological in origin and led to a reinvigoration of the study of such conditions via modern scientific techniques. Whether the enlargement of the ventricles is a cause or a result of schizophrenia has not yet been ascertained, however. Still, this founding was not revolutionary at the time, as enlarged ventricles are found in various other types of organic dementia. In fact, ventricle volumes have been found to be "mainly explained by environmental factors" and to be extremely diverse between individuals, such that the percentage difference in group averages in schizophrenia studies (+16%) has been described as "not a very profound difference in the context of normal variation" (ranging from 25% to 350% of the mean average). Nowadays, magnetic resonance imaging (MRI) has superseded the use of CT in research into the role of ventricular abnormalities in psychiatric illness.
Read more about this topic: Ventricular System
Famous quotes containing the words role in, disorder, role and/or disease:
“If womens role in life is limited solely to housewife/mother, it clearly ends when she can no longer bear more children and the children she has borne leave home.”
—Betty Friedan (20th century)
“Without metaphor the handling of general concepts such as culture and civilization becomes impossible, and that of disease and disorder is the obvious one for the case in point. Is not crisis itself a concept we owe to Hippocrates? In the social and cultural domain no metaphor is more apt than the pathological one.”
—Johan Huizinga (18721945)
“Friends serve central functions for children that parents do not, and they play a critical role in shaping childrens social skills and their sense of identity. . . . The difference between a child with close friendships and a child who wants to make friends but is unable to can be the difference between a child who is happy and a child who is distressed in one large area of life.”
—Zick Rubin (20th century)
“Anti-Semitism is a horrible disease from which nobody is immune, and it has a kind of evil fascination that makes an enlightened person draw near the source of infection, supposedly in a scientific spirit, but really to sniff the vapors and dally with the possibility.”
—Mary McCarthy (19121989)