Ventral Tegmental Area

The ventral tegmentum (tegmentum is Latin for covering), better known as the ventral tegmental area (VTA), is a group of neurons located close to the midline on the floor of the midbrain (mesencephalon). The VTA is the origin of the dopaminergic cell bodies of the mesocorticolimbic dopamine system and is widely implicated in the drug and natural reward circuitry of the brain. It is important in cognition, motivation, drug addiction, intense emotions relating to love, and several psychiatric disorders. The VTA contains neurons that project to numerous areas of the brain, from the prefrontal cortex (PFC) to the caudal brainstem and several regions in between.

Read more about Ventral Tegmental Area:  Anatomy, Outputs, Inputs, Limbic Loop, CA3 Loop, Reward System

Other articles related to "ventral tegmental area, areas":

Conditioned Place Preference - Pharmacological Effects - Cholinergic Drugs - Nicotine
... reinforcing effects of nicotine has been implicated in acetycholines projection to the ventral tegmental area ... There are nAChRs in the ventral tegmental area, which is one of the main sites of dopamine production and it projects dopamine through the mesolimbic system ... The projection from the ventral tegmental area to the nucleus accumbens has been primarily studied and associated with reward ...
Ventral Tegmental Area - Clinical Relevance - Drug Addiction
... Experiments in rats have shown that animals learn to press a lever for the administration of drugs such as nicotine, carbachol, opiates, cocaine, and ethanol into the posterior VTA more readily than into the anterior VTA ... Other studies have shown that microinjections of dopaminergic drugs into the NAC shell increase locomotor activity and exploratory behaviors, conditioned approach responses, and anticipatory sexual behaviors ...
Dopamine - Functions in The Brain - Anatomy
... neurotransmitter system which originates in substantia nigra pars compacta, ventral tegmental area (VTA), and hypothalamus ... These project axons to large areas of the brain which are typically divided into four major pathways Mesocortical pathway connects the ventral tegmental area to the frontal lobe of the pre-frontal ... Neurons with somas in the ventral tegmental area project axons into the pre-frontal cortex ...

Famous quotes containing the word area:

    Self-esteem is the real magic wand that can form a child’s future. A child’s self-esteem affects every area of her existence, from friends she chooses, to how well she does academically in school, to what kind of job she gets, to even the person she chooses to marry.
    Stephanie Martson (20th century)