UDP-glucose 4,6-dehydratase

In enzymology, an UDP-glucose 4,6-dehydratase (EC 4.2.1.76) is an enzyme that catalyzes the chemical reaction

UDP-glucose UDP-4-dehydro-6-deoxy-D-glucose + H2O

Hence, this enzyme has one substrate, UDP-glucose, and two products, UDP-4-dehydro-6-deoxy-D-glucose and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include UDP-D-glucose-4,6-hydrolyase, UDP-D-glucose oxidoreductase, and UDP-glucose 4,6-hydro-lyase. This enzyme participates in nucleotide sugars metabolism.