|Molecular function||• DNA binding
• protein binding
|Cellular component||• nucleoplasm
|Biological process||• blastocyst growth
• regulation of transcription from RNA polymerase I promoter
• transcription from RNA polymerase I promoter
• transcription initiation from RNA polymerase I promoter
• transcription elongation from RNA polymerase I promoter
• termination of RNA polymerase I transcription
• embryo implantation
• gene expression
• positive regulation of transcription from RNA polymerase I promoter
|Sources: Amigo / QuickGO|
42.28 – 42.3 Mb
102.3 – 102.32 Mb
Nucleolar transcription factor 1 is a protein that in humans is encoded by the UBTF gene.
Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and three TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990).
Read more about UBTF: Interactions
Other articles related to "ubtf":
... UBTF has been shown to interact with Casein kinase 2, alpha 1, TAF1C, Retinoblastoma protein and TAF1 ...