Troponin

Troponin is a complex of three regulatory proteins (troponin C, troponin I and troponin T) that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle.

Discussions of troponin often pertain to its functional characteristics and/or to its usefulness as a diagnostic marker for various heart disorderss.

Read more about TroponinFunction, Physiology, Diagnostic Use, Relation With Contractile Function and Heart Failure

Other articles related to "troponin":

Troponin - Relation With Contractile Function and Heart Failure
... Mutations in the cardiac troponin subunits can result in cardiomyopathies, including familial hypertrophic cardiomyopathy ...
Troponin Test - Function
... Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue ... Some of this calcium attaches to troponin which causes it to change shape, exposing binding sites for myosin (active sites) on the actin filaments ... Troponin is found in both skeletal muscle and cardiac muscle, but the specific versions of troponin differ between types of muscle ...
Troponin Test
... Troponin is a complex of three regulatory proteins (troponin C, troponin I and troponin T) that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle ... Discussions of troponin often pertain to its functional characteristics and/or to its usefulness as a diagnostic marker or therapeutic target for various heart disorders ...
Troponin Test - Physiology
... Troponin is a component of thin filaments (along with actin and tropomyosin), and is the protein complex to which calcium binds to trigger the ... Troponin itself has three subunits, TnC, TnI, and TnT, each of which play a role in force regulation ... Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro ...
TNNC2
... function • actin binding • calcium ion binding Cellular component • cytosol • troponin complex Biological process • skeletal muscle ... Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits ... while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments ...