Trka

Some articles on trka:

Trk A Receptor - The Low Affinity Nerve Growth Factor Receptor
... There is one other NGF receptor besides TrkA, called the "LNGFR" (for "Low Affinity Nerve Growth Factor Receptor") ... As opposed to TrkA, the LNGFR plays a somewhat less clear role in NGF biology ... however, that in the absence of a co-expressed TrkA, the LNGFR may signal a cell to die via apoptosis – so therefore cells expressing the LNGFR in the absence of Trk ...
Trk Receptor - Regulation By P75NTR - TrkA and TrkB Receptors Activity Are Ligand-dependent
... To test if TrkA and TrkB receptors activity are ligand-dependent, the receptors are treated with NGF and BDNF correspondingly ... On the other hands, PC12 cells were treated with NGF, since it expresses more TrkA and p75NTR but not TrkB and TrkC ... rapidly with the presence of BDNF compared with control (absence of BDNF) whereas TrkA phosphotyrosine content increased modestly when treated with ...
Trk Receptor Types and Corresponding Ligands - TrkA
... TrkA has the highest affinity to the binding nerve growth factor (NGF) ... Nociceptive sensory neurons express mostly trkA and not trkB or trkC ...
Nerve Growth Factor Receptor - TrkA, B, and C Receptors
... TrkA is a receptor tyrosine kinase (meaning it mediates its actions by causing the addition of phosphate molecules on certain tyrosines in the cell, activating cellular signaling) ... neurotrophic factors structurally related to NGF (BDNF, NT-3, and NT-4) TrkA mediates the effects of NGF TrkB binds and is activated by BDNF, NT-4, and NT-3 TrkC binds and is activated only by NT-3 ...
Low-affinity Nerve Growth Factor Receptor - The Neurotrophins
... cells, binds to and activates its high-affinity receptor (TrkA), and is internalized into the responsive neuron ... The NGF/TrkA complex is subsequently trafficked back to the cell body ... The activation of TrkA by NGF is critical in inducing the survival and differentiation caused by this growth factor ...