Trinucleotide

Some articles on trinucleotide:

Trinucleotide Repeat Disorders - Genetics - Why Three Nucleotides?
... Trinucleotide repeat expansions tend to be near coding regions of the genome, and therefore repeats that are not multiples of three could cause frameshift mutations ... the expression of developmentally obligatory pathways, then non-trinucleotide repeats may be masked by developmental lethality ... cases render the protein coded for useless - a trinucleotide addition to a gene can have no effect at all on the protein, can cripple the protein, or sometimes can make it work even better than it used to ...
List Of Y-STR Markers - Mutation Rates
... It appears that some trinucleotide markers may have much higher mutation rates at some repeat lengths than at others ... For example, variation of the trinucleotide DYS388 is generally very slow in most haplogroups, when it takes the values 11-13 ... Similarly the trinucleotide DYS392 is reported to be "fast" in haplogroups N and Q, where it takes values 14-16 which are rare in other groups ...
Trinucleotide Repeat Disorders
... Trinucleotide repeat disorders (also known as trinucleotide repeat expansion disorders, triplet repeat expansion disorders or codon reiteration disorders) are a ... Trinucleotide repeats are sometimes classified as insertion mutations and sometimes as a separate class of mutations ...
Trinucleotide Repeat Expansion
... Trinucleotide repeat expansion, also known as triplet repeat expansion, is the DNA mutation responsible for causing any type of disorder categorized as a trinucleotide repeat disorder ... This property results in the characteristic of anticipation seen in trinucleotide repeat disorders ... a new disease model was produced to explain the progression of Huntington's Disease and similar trinucleotide repeat disorders, which, in simulations, seems to accurately predict age of onset and the way the ...
Huntington's Disease - Genetics - Genetic Mutation
... HD is one of several trinucleotide repeat disorders which are caused by the length of a repeated section of a gene exceeding a normal range ... CAGCAGCAG...), known as a trinucleotide repeat ... Classification of the trinucleotide repeat, and resulting disease status, depends on the number of CAG repeats Repeat count Classification Disease status ...