Toscana Virus - Virology - Structure and Genome

Structure and Genome

TOSV has a spherical, enveloped body with a 80-120 nm in diameter. The genome is encases in a nucleocapsid and consists of negative-sense RNA broken into three segments, termed L, M and S. L is about 6,400 nucleotides in length, M about 4,200 nucleotides in length, and S about 1,900 nucleotides in length. L encodes for the viral polymerase, M encodes for structural glycoproteins and S encodes for nucleic proteins.

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