Sickle cell trait (or sicklemia) describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both normal and abnormal hemoglobin (the two alleles are co-dominant). Sickle cell disease is a blood disorder in which the body produces an abnormal type of the oxygen-carrying substance hemoglobin in the red blood cells. Sickling and sickle cell disease also confer some resistance to malaria parasitization of red blood cells, so that individuals with sickle-cell trait (heterozygotes) have a selective advantage in some environments.
Other articles related to "cell, sickle, traits, cells, trait, sickle cell, sickle cell trait":
... Prison cell, a room used to hold people in prisons Cell, a unit of a clandestine cell system, a penetration-resistant form of a secret or outlawed organization Cell, a group of people ...
... Sickle-cell conditions are inherited from parents in much the same way as blood type, hair color and texture, eye colour, and other physical traits ... The types of haemoglobin a person makes in the red blood cells depend on what haemoglobin genes are inherited from his parents ... If one parent has sickle-cell anaemia (SS) and the other has sickle-cell trait then there is a 50% chance of a child's having sickle-cell disease and a 50% chance of a child's having sickle-cell trait ...
... Further information Genetic resistance to malaria Individuals with sickle cell anemia or sickle cell trait do have reduced parasitemia when compared to wild-typed individuals for the ... and reproduce by invading red blood cells ... The process of bursting red blood cells does not have any symptoms, however destruction of the cells does cause anemia, since the bone marrow cannot compensate for the damage ...
... Baden said, "Preliminary findings indicate the boy did not die from sickle cell trait, nor did he die from natural causes." Dr ... Baden has said repeatedly that sickle trait by itself does not cause death ... He explained a "sickle cell crisis" is a sickle cell disease - not the same as sickle cell trait ...
Famous quotes containing the words trait and/or cell:
“I am the family face;
Flesh perishes, I live on,
Projecting trait and trace
Through time to times anon,
And leaping from place to place
—Thomas Hardy (18401928)
“Why inspire in us a horror of our being?... To look upon the universe as a prison cell and all men as criminals about to be executed is the idea of a fanatic.”
—Voltaire [François Marie Arouet] (16941778)