|Molecular function||• nucleic acid binding
• protein binding
• zinc ion binding
|Cellular component||• nucleus
• spliceosomal complex
• nuclear speck
• catalytic step 2 spliceosome
|Biological process||• RNA splicing, via transesterification reactions
• mRNA 3'-splice site recognition
• mRNA splicing, via spliceosome
• mRNA processing
• RNA splicing
• gene expression
|Sources: Amigo / QuickGO|
38.42 – 38.46 Mb
124.71 – 124.73 Mb
Splicing factor 3A subunit 3 is a protein that in humans is encoded by the SF3A3 gene.
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.
Read more about SF3A3: Interactions
Other articles related to "sf3a3":
... SF3A3 has been shown to interact with SF3A1. ...