Primate Basal Ganglia System - Regulators of The Basal Ganglia Core - Subthalamic Nucleus, or Corpus Lyuisi - Subthalamo-lateropallidal Pacemaker

Subthalamo-lateropallidal Pacemaker

As said before, the lateral pallidum has purely intrinsic basal ganglia targets. It is particularly linked to the subthalamic nucleus by two-way connections. Contrary to the two output sources (medial pallidum and nigra reticulata), neither the lateral pallidum or the subthalmic nucleus send axons to the thalamus. The subthalamic nucleus and lateral pallidum are both fast-firing pacemakers. Together they constitute the "central pacemaker of the basal ganglia" with synchronous bursts. The pallido-subthalamic connection is inhibitory, the subthalamo-pallidal is excitatory. They are coupled regulators or coupled autonomous oscillators, the analysis of which has been insufficiently deepened. The lateral pallidum receives a lot of striatal axons, the subthalamic nucleus not. The subthalamic nucleus receives cortical axons, the pallidum not. The subsystem they make with their inputs and outputs corresponds to a classical systemic feedback circuit but it is evidently more complex.

Read more about this topic:  Primate Basal Ganglia System, Regulators of The Basal Ganglia Core, Subthalamic Nucleus, or Corpus Lyuisi