Placental growth factor is a protein that in humans is encoded by the PGF gene.
Placental growth factor (PGF) is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast.
Other articles related to "placental growth factor, growth, placental":
... Placental growth factor-expression within human atherosclerotic lesions is associated with plaque inflammation and neovascular growth ... In addition, placental sFlt-1 levels were significantly increased and PGF decreased in women with preeclampsia as compared to those with uncomplicated pregnancies ... This suggests that placental concentrations of sFlt-1 and PGF mirror the maternal serum changes ...
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