Phosphocholine

Phosphocholine is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP and choline into phosphocholine and ADP. Phosphocholine is a molecule found for example in lecithin.

It is also used by nematodes and human placentas as a posttranslational modification to suppress an immune response by their hosts.

It is also one of the binding targets of C-reactive protein (CRP). Thus when a cell is damaged, CRP binds to phosphocholine beginning the recognition and phagocytotic immunologic response.

Phosphocholine is one of the natural constituents of hens' eggs (and many other eggs) which is often used in biomimetic membrane studies.

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Other articles related to "phosphocholine":

Alkenylglycerophosphocholine Hydrolase
... that catalyzes the chemical reaction 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O an aldehyde + sn-glycero-3-phosphocholine Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-p ... name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase ...
Phosphatidylcholine Desaturase
... EC 1.3.1.35) is an enzyme that catalyzes the chemical reaction 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD+ 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH + H+ Thus, the two ...
Phosphatidylcholine 12-monooxygenase
... that catalyzes the chemical reaction 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + H+ + O2 1-acyl-2--sn-glycero-3-phosphocholine + NAD+ + H2O The 4 substrates of this enzyme are 1-acyl-2-oleoyl-s ... name of this enzyme class is 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADHoxygen oxidoreductase (12-hydroxylating) ...
1-alkyl-2-acetylglycerophosphocholine Esterase
... enzyme that catalyzes the chemical reaction 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O 1-alkyl-sn-glycero-3-phosphocholine + acetate Thus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycer ... The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase ... Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPCacetylhydrolase ...