Penbutolol

Penbutolol (Levatol, Levatolol, Lobeta, Paginol, Hostabloc, Betapressin) is a medication in the class of beta blockers, used in the treatment of high blood pressure. Penbutolol is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective β blocker . Penbutolol is a sympathomimetic drug with properties allowing it to act as a partial agonist at β adrenergic receptors . Penbutolol has also been found to be one of very few compounds that are 5-HT1A antagonists. 5-HT1A receptors are activated by serotonin, which have many different actions in different species. This makes it difficult to create generalizations about serotonin and its effects .

Read more about PenbutololHypertension, β1 Blockade, Characteristics

Other articles related to "penbutolol":

Lobeta - Characteristics
... Penbutolol is typically administered orally in doses of 20 mg per day ... Penbutolol has a half life of five hours, and a low frequency of side effects ... When penbutolol is being metabolized, it undergoes a series of biotransformations, the main one being hydroxylation ...
Lobeta - β1 Blockade
... Penbutolol acts on the β1 adrenergic receptors in both the heart and the kidney ... Penbutolol blocks this and decreases heart rate, which lowers blood pressure ... The ability of penbutolol to act as a partial agonist proves useful in the prevention of bradycardia as a result of decreasing the heart rate excessively ...
Penbutolol - Characteristics
... Penbutolol is typically administered orally in doses of 20mg per day ... Penbutolol has a half life of five hours, and a low frequency of side effects ... When penbutolol is being metabolized, it undergoes a series of biotransformations, the main one being hydroxylation ...