Parp

Some articles on parp, parps:

PARP2
... Identifiers Symbols PARP2 ADPRT2 ADPRTL2 ADPRTL3 ARTD2 PARP-2 pADPRT-2 External IDs OMIM 607725 MGI 1341112 HomoloGene 4004 ChEMBL 5366 GeneCards PARP2 Gene EC number 2.4.2.3 ...
Homologous Recombination - Technological Applications - Cancer Therapy
... By stopping DNA repair in such a fashion, olaparib applies the concept of synthetic lethality to specifically target cancer cells ... Exploiting synthetic lethality is a new direction in anti-cancer drug development ...
PARP10
... Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones ... PARPs can also function as transcriptional cofactors (Yu et al ...
PARP1 - Function
... conjunction with BRCA, which acts on double strands members of the PARP family act on single strands or, when BRCA fails, PARP takes over those jobs as well ...
TNKS2
... Identifiers Symbols TNKS2 ARTD6 PARP-5b PARP-5c PARP5B PARP5C TANK2 TNKL pART6 External IDs OMIM 607128 MGI 1921743 HomoloGene 11890 ChEMBL 6154 GeneCards TNKS2 Gene EC number 2.4.2.30 Gene Ontology Molecular ...