Opioid Receptor

Opioid Receptor

Opioid receptors are a group of G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs). Opiate receptors are distributed widely in the brain, and are found in the spinal cord and digestive tract.

Read more about Opioid Receptor:  Discovery, Purification, Major Subtypes, Naming, Additional Receptors, Pathology

Other articles related to "opioid receptor, receptors, opioid, receptor, opioids, opioid receptors":

Met-enkephalin - Pharmacology - Pharmacodynamics
... enkephalin is a potent agonist of the δ-opioid receptor, and to a lesser extent the μ-opioid receptor, with little to no effect on the κ-opioid receptor ... It is through these receptors that enkephalin produces its opioid effects, such as analgesia and mood lift ... It is also the endogenous ligand of the opioid growth factor receptor (OGFR formerly known as the ζ-opioid receptor), which plays a role in the regulation of tissue growth and regeneration hence why enkephalin is ...
Sigma Receptor - Classification
... Sigma receptors were once thought to be a type of opioid receptor, because the d- stereoisomers of the benzomorphan class of opioid drugs reduced coughing, as do some other opioid derivatives such as dextromethorphan ... However, such drugs had no effects at μ (Mu Opioid receptor), κ (Kappa Opioid receptor), or δ (Delta Opioid receptor) receptors ... pharmacological testing indicated that the sigma receptors were activated by drugs completely unrelated to the opioids, and their function was unrelated to the function of the opioid ...
Opioid Receptor - Pathology
... Some forms of mutations in δ-opioid receptors have resulted in constant receptor activation ...
Delta Opioid Receptor
... protein binding • enkephalin receptor activity Cellular component • cytoplasm • plasma membrane • integral to plasma membrane • vesicle • dendrite membrane • axon ...
... Cyprodime is an opioid antagonist from the morphinan family of drugs ... Cyprodime is a selective opioid antagonist which blocks the μ-opioid receptor, but without affecting the δ-opioid or κ-opioid receptors ... This makes it useful for scientific research as it allows the μ-opioid receptor to be selectively deactivated so that the actions of the δ and κ receptors can be studied separately ...

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