Operon

In genetics, an operon is a functioning unit of genomic DNA containing a cluster of genes under the control of a single regulatory signal or promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo trans-splicing to create monocistronic mRNAs that are translated separately, i.e. several strands of mRNA that each encode a single gene product. The result of this is that the genes contained in the operon are either expressed together or not at all. Several genes must be both co-transcribed and co-regulated to define an operon.

Originally, operons were thought to exist solely in prokaryotes, but since the discovery of the first operons in eukaryotes in the early 1990s, more evidence has arisen to suggest they are more common than previously assumed.

Read more about Operon:  History, Overview, As A Unit of Transcription, General Structure of An Operon, Regulation, The lac Operon, The trp Operon, Predicting The Number and Organization of Operons

Other articles related to "operon, operons":

Acetolactate Synthase - Regulation
... Each subunit pair is located on its own operon ... Together, these operons code for several enzymes involved in branched-chain amino acid biosynthesis ... Regulation is different for each operon ...
Leucine Operon Leader
... The Leucine operon leader is an RNA element found upstream of the first gene in the Leucine biosynthetic operon ... The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed ... allows RNA polymerase to transcribe the operon ...
Predicting The Number and Organization of Operons
... The number and organization of operons has been studied most critically in E ... frames as a primary predictor of the number of operons in the genome ... Longer stretches exist where operons start and stop, often up to 40–50 bases ...
L-arabinose Operon
... The -arabinose operon, also called ara operon, is a gene sequence encoding enzymes needed for the catabolism of arabinose to xylulose 5-phosphate, an intermediate of the pentose phosphate pathway ... The operon is found in Escherichia coli ...
Allolactose
... It is an inducer of the lac operon in Escherichia coli ... The absence of the repressor allows the transcription of the lac operon to proceed ... (IPTG), is normally used in molecular biology to induce the lac operon ...