The deletion of the 48 copies of the C/D box snoRNA SNORD116 has been shown to be the primary cause of Prader–Willi syndrome. Prader–Willi is a developmental disorder associated with over-eating and learning difficulties. SNORD116 has potential target sites within a number of protein-coding genes, and could have a role in regulating alternative splicing.
Other articles related to "syndrome":
... Despite the rarity of Prader-Willi syndrome, it has become widely-known in wider society and often depicted in popular culture, partly due to the fascination ... Prader-Willi syndrome has been depicted and documented several times in television ... An individual with Prader-Willi Syndrome featured in the episode entitled "Dog Eat Dog" of the television series CSI Crime Scene Investigation (aired on November 24, 2005) ...
Famous quotes containing the word syndrome:
“[T]he syndrome known as life is too diffuse to admit of palliation. For every symptom that is eased, another is made worse. The horse leechs daughter is a closed system. Her quantum of wantum cannot vary.”
—Samuel Beckett (19061989)