MYH11 - Acute Myeloid Leukemia

Acute Myeloid Leukemia

The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N-terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype.

Read more about this topic:  MYH11

Other articles related to "leukemia, acute myeloid leukemia, acute, myeloid leukemia, leukemias":

Myeloid Sarcoma - Frequency and Patterns of Presentation - In Acute Leukemia
... seen even by physicians specializing in the treatment of leukemia ... with the above risk factors, chloroma remains an uncommon complication of acute myeloid leukemia ... develop as the sole manifestation of relapse after apparently successful treatment of acute myeloid leukemia ...
Acute Myeloid Leukemia - In Pregnancy
... Leukemia is rarely associated with pregnancy, affecting only about 1 in 10,000 pregnant women ... How it is handled depends primarily on the type of leukemia ... Acute leukemias normally require prompt, aggressive treatment, despite significant risks of pregnancy loss and birth defects, especially if chemotherapy is given during the ...
Mir-10 Micro RNA Precursor Family - Association With Cancer
... Downregulation of miR-10a has been found in chronic myeloid leukemia ... USF2, a target gene of miR-10a, has been found to be overexpressed in these leukemias ... of miR-10a has also been found in acute myeloid leukemia, the most common acute leukemia affecting adults ...

Famous quotes containing the word acute:

    I find the pain of a little censure, even when it is unfounded, is more acute than the pleasure of much praise.
    Thomas Jefferson (1743–1826)