Mohs Surgery

Mohs surgery, also known as chemosurgery, developed in 1938 by a general surgeon, Dr. Frederic E. Mohs, is microscopically controlled surgery used to treat common types of skin cancer. During the surgery, after each removal of tissue, while the patient waits, the pathologist examines the tissue specimen for cancer cells, and that examination informs the surgeon where to remove tissue next. Mohs surgery is one of the many methods of obtaining complete margin control during removal of a skin cancer (CCPDMA – complete circumferential peripheral and deep margin assessment.) using frozen section histology. CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.

The cure rate with Mohs surgery cited by most studies is between 97% and 99.8% for primary basal cell carcinoma, the most common type of skin cancer. Mohs procedure is also used for squamous cell carcinoma, but with a lower cure rate. Two isolated studies reported cure rate for primary basal cell carcinoma as low as 95% and 96% (see the discussion below titled "Why is the Cure Rate so Varied?). Recurrent basal cell cancer has a lower cure rate with Mohs surgery, more in the range of 94%. It has been used in the removal of melanoma-in-situ (cure rate 77% to 98% depending on surgeon), and certain types of melanoma (cure rate 52%). Another study of melanoma-in-situ revealed Mohs cure rate of 95% for frozen section Mohs, and 98 to 99% for fixed tissue Mohs method.

Other indications for Mohs surgery include dermatofibrosarcoma protuberans, keratoacanthoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, merkel cell carcinoma, Paget's disease of the breast, atypical fibroxanthoma, leiomyosarcoma, and angiosarcoma. Because the Mohs procedure is micrographically controlled, it provides precise removal of the cancerous tissue, while healthy tissue is spared. Mohs surgery is relatively expensive when compared to other surgical modalities. However, in anatomically important areas (eyelid, nose, lips), tissue sparing and low recurrence rate makes it a procedure of choice by many physicians.

Read more about Mohs Surgery:  History, Mohs Procedure, Differences Between Histology of Transverse Sections and Vertical Sections, Mohs Surgery and Blood Thinner, The Mohs Surgery Team, Why Is The Cure Rate So Varied?, Comparison To Other Modalities of Treatment, Controversy About Mohs Surgery, Where Mohs Surgery Is Allowed, Future Applications of Mohs Surgery, Associations

Other articles related to "mohs surgery, mohs, surgery":

Basal-cell Carcinoma - Treatment - Mohs Surgery
... Mohs surgery (or Mohs micrographic surgery) is an outpatient procedure in which the tumor is surgically excised and then immediately examined under a microscope ... carcinoma however, the cure rate is not as high as Mohs surgery for basal-cell carcinoma ...
Skin Cancer - Management
... in a young person, the treatment with the best cure rate (Mohs surgery or CCPDMA) might be indicated ... disease both, however, may have lower overall cure rates than certain type of surgery ... Mohs' micrographic surgery (Mohs surgery) is a technique used to remove the cancer with the least amount of surrounding tissue and the edges are checked immediately to see if tumor is found ...
Mohs Surgery - Associations
... The American College of Mohs Surgery is the organization that sets standards of care for fellowship trained Mohs surgeons who perform Mohs surgery as a primary function of their practice ... ACMS fellowship require 1 to 2 years of training in the Mohs procedure including reconstructive and plastic surgery – in addition to 4 years of residency ... The American Society of Mohs Surgery is an organization of dermatologists who perform dermatology and Mohs surgery in their practice ...
Melanoma - Treatment - Surgery
... biopsies may remove the tumor, but further surgery is often necessary to reduce the risk of recurrence ... excision of melanoma-in-situ, but 0.2 cm margin might be acceptable for margin controlled surgery (Mohs surgery, or the double-bladed technique with margin ... Mohs surgery has been reported with cure rate as low as 77% and as high as 98% for melanoma-in-situ ...
Basal-cell Carcinoma - Treatment - Standard Surgical Excision
... On the face, or on recurrent basal-cell cancer after previous surgery, special surgical margin controlled processing (CCPDMA - complete circumferential ... a patient should demand that either Mohs surgery or frozen section histology with either margin control (ccpdma) or thin serial bread-loafing is utilized when ... the tissue utilizing a method approximating the Mohs method (described in most basic histopathology text books or described in this reference ) during frozen section processing ...

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