Microcephaly

Microcephaly is a neurodevelopmental disorder in which the circumference of the head is more than two standard deviations smaller than average for the person's age and sex. Microcephaly may be congenital or it may develop in the first few years of life. The disorder may stem from a wide variety of conditions that cause abnormal growth of the brain, or from syndromes associated with chromosomal abnormalities. Two copies of a loss-of-function mutation in one of the microcephalin genes causes primary microcephaly.

In general, life expectancy for individuals with microcephaly is reduced and the prognosis for normal brain function is poor. The prognosis varies depending on the presence of associated abnormalities.

Read more about Microcephaly:  Causes, Presentation, Prognosis, History, Notable Microcephalic Persons

Other articles related to "microcephaly":

Dubowitz Syndrome - Microcephaly
... Microcephaly is a characteristic in which the circumference of the head is smaller than normal due to improper development of the brain ... cerebral cortex lead to many of the features associated with microcephaly ... Microcephaly has a wide range of prognoses some patients experience very little mental retardation and can reach regular age-appropriate milestones, while others experience severe mental retardation and neuromuscular ...
Craniosynostosis - Differential Diagnosis - Primary Microcephaly
... Primary microcephaly shows a clinical image of craniosynostosis, but due to a different cause ... spaces are typically enlarged with primary microcephaly, whereas they are reduced or absent in true pansynostosis ...
Microcephaly - Notable Microcephalic Persons
... William Henry Johnson) is commonly associated with microcephaly, although he may not have actually had it ...
Microcephalic - Causes - Other
... Microcephaly can also be associated with other conditions that are only indirectly associated with the nervous system alcoholism (which can result in the fetal alcohol syndrome disability ... Microcephaly prevalence was 7 out of a group of 11 pregnant women at 11–17 weeks of gestation who survived the blast at less than 1.2 km from ground zero ... Microcephaly is the only proven malformation, or congenital abnormality, found in the children of Hiroshima and Nagasaki ...
Microcephalic - Causes
... Microcephaly is a type of cephalic disorder ... A genetic factor may play a role in causing some cases of microcephaly ... side a relation has been found between schizophrenia, deletions of chromosomes and microcephaly ...