Methyltransferases

Some articles on methyltransferases, methyltransferase:

DMNT - Classification - De Novo and maintenance DNA MTases
... De novo methyltransferases recognize something in the DNA that allows them to newly methylate cytosines ... Maintenance methyltransferases add methylation to DNA when one strand is already methylated ... to maintain the methylation pattern that had been established by the de novo methyltransferases IS ...
DMNT - Classification - EC Classification
... EC 2.1.1.113 m5C - those that generate C5-methylcytosine EC 2.1.1.37 m6A and m4C methyltransferases are found primarily in prokaryotes ... m6A methyltransferases (N-6 adenine-specific DNA methylase) (A-Mtase) are enzymes that specifically methylate the amino group at the C-6 position of adenines in DNA ... The M (hsdM) and S subunits together form a methyltransferase that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence ...
Histone Methyltransferase
... Histone methyltransferases (HMT) are histone-modifying enzymes, (including histone-lysine N-methyltransferase and histone-arginine N-methyltransferase), that catalyze the transfer of one, two, or three methyl groups ... In both types of histone methyltransferases, cofactor S-Adenosyl methionine (SAM) serves as a cofactor and methyl donor group ... of DNA and histone proteins), so enzymes, such as histone methyltransferases, must overcome this inaccessibility ...
Methylation - In Biology - Epigenetics
... of Me-CpG is catalyzed by the enzyme DNA methyltransferase ... (symmetric dimethylated arginine) by peptidylarginine methyltransferases (PRMTs) ... Lysine can be methylated once, twice or three times by lysine methyltransferases ...
DNA Methylation - DNA Methyltransferases
... Without the DNA methyltransferase (DNMT), the replication machinery itself would produce daughter strands that are unmethylated and, over time, would lead to passive demethylation ... DNMT1 is the proposed maintenance methyltransferase that is responsible for copying DNA methylation patterns to the daughter strands during DNA replication ... It is thought that DNMT3a and DNMT3b are the de novo methyltransferases that set up DNA methylation patterns early in development ...