When an event occurs which causes the bundle of cilia to deflect toward the taller side, ion channels open, and a depolarization of the cell is caused by the inward current which results. This is known as a positive deflection. This process involves the stretching of tip links, which pull the ion channels open. A deflection in the opposite direction is termed negative deflection, and causes tip links to relax and the ion channels to close. Perpendicular deflection is ineffective. It is suspected that the site of transduction channels is at the stereocilia tips. The speed with which ion channels respond to deflection leads researchers to believe that mechanical stimuli act directly upon the ion channel, and do not need a second messenger. The sensitivity of cilia is primarily due to ciliary length. The stereocilia of functional hair cells have the ability to convert mechanical deflections to neural signals.
Other articles related to "function":
... Let f be a continuous real-valued function defined on a closed interval ... Let F be the function defined, for all x in, by Then, F is continuous on, differentiable on the open interval (a, b), and for all x in (a, b) ... Let f be a real-valued function defined on a closed interval that admits an antiderivative g on ...
... is the statement that differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original function is retrieved ... allows one to compute integrals by using an antiderivative of the function to be integrated ...
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance, a vector in R3 ... Just as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the double integral ... The same volume can be obtained via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between the surface and the ...
Famous quotes containing the word function:
“The art of living is to function in society without doing violence to ones own needs or to the needs of others. The art of mothering is to teach the art of living to children.”
—Elaine Heffner (20th century)
“Our father has an even more important function than modeling manhood for us. He is also the authority to let us relax the requirements of the masculine model: if our father accepts us, then that declares us masculine enough to join the company of men. We, in effect, have our diploma in masculinity and can go on to develop other skills.”
—Frank Pittman (20th century)
“To look backward for a while is to refresh the eye, to restore it, and to render it the more fit for its prime function of looking forward.”
—Margaret Fairless Barber (18691901)