Mast Cell

A mast cell (also known as mastocyte and labrocyte) is a resident cell of several types of tissues and contains many granules rich in histamine and heparin. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing and defense against pathogens.

The mast cell is very similar in both appearance and function to the basophil, a type of white blood cell. However, they are not the same, as they both arise from different cell lines.

Read more about Mast CellOrigin and Classification, Physiology, Histological Staining

Other articles related to "mast cell, mast cells, cell, cells":

Mast Cell Leukemia - Therapy
... Immunoglobulin E (IgE) is important in mast cell function ... raised in sheep resulted in a transient decrease in the numbers of circulating mast cells in one patient with mast cell leukemia ... Although splenectomy has led to brief responses in patients with mast cell leukemia no firm conclusions as to the efficacy of this treatment are possible ...
Mast Cell Stabilizer
... Mast cell stabilizers are cromone medications used to prevent or control certain allergic disorders ... They block a calcium channel essential for mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators ... Without intracellular calcium, the histamine vesicles cannot fuse to the cell membrane and degranulate ...
CD117
... protein tyrosine kinase activity • stem cell factor receptor activity • protein binding • ATP binding • cytokine binding • protein homodimerization activity • metal ion binding ...
Mast Cell - Histological Staining
... common stains for acid mucopolysaccharides and glycoaminoglycans, components of mast cells granules ... Surface markers - Cell surface markers of mast cells were referred in detail by Heneberg, claiming that mast cells may be inadverently included in the stem or ... The classical mast cell markers include the high affinity IgE receptor, CD25 (non-neoplastic mast cells), CD117 (c-Kit), CD23 and CD203c (for most of the mast cell populations) ...
Santa J. Ono - Scientific Career
... MHC gene products are expressed at higher levels or de novo on the insulin-producing beta cells of the islets of Langerhans ... This has turned out to be relevant to the developmental control of B cell differentiation ... More recently, his laboratory determined the role of beta-chemokines in mast cell-dependent inflammation in the ocular surface ...

Famous quotes containing the words cell and/or mast:

    There’s not one part of his physical being that’s like that of human beings. From his warped brain down to the tiniest argumentative cell of his huge carcass, he’s unearthly.
    —Willis Cooper. Rowland V. Lee. Wolf von Frankenstein (Basil Rathbone)

    To coöperate in the highest as well as the lowest sense, means to get our living together. I heard it proposed lately that two young men should travel together over the world, the one without money, earning his means as he went, before the mast and behind the plow, the other carrying a bill of exchange in his pocket. It was easy to see that they could not long be companions or coöperate, since one would not operate at all. They would part at the first interesting crisis in their adventures.
    Henry David Thoreau (1817–1862)