Magnetofection - Biodistribution of Magnetic Nanoparticles

Biodistribution of Magnetic Nanoparticles

The biodegradable cationic magnetic nanoparticles are not toxic at the recommended doses and even higher doses. Gene vectors / magnetic nanoparticles complexes are seen into cells after 10–15 minutes that is much faster than any other transfection method. After 24, 48 or 72 hours, most of the particles are localized in the cytoplasm, in vacuoles (membranes surrounded structure into cells) and occasionally in the nucleus.

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    We are in great haste to construct a magnetic telegraph from Maine to Texas; but Maine and Texas, it may be, have nothing important to communicate.
    Henry David Thoreau (1817–1862)