Lysine

Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. It is an essential amino acid for humans. Lysine's codons are AAA and AAG.

Lysine is a base, as are arginine and histidine. The ε-amino group often participates in hydrogen bonding and as a general base in catalysis. (The ε-amino group (NH3+) is attached to the fifth carbon beginning from the α-carbon, which is attached to the carboxyl (C=OOH) group.)

Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications at lysine residues include acetylation and ubiquitination. Collagen contains hydroxylysine, which is derived from lysine by lysyl hydroxylase. O-Glycosylation of hydroxylysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.

Read more about LysineBiosynthesis, Metabolism, Synthesis, Dietary Sources, Properties, Clinical Significance, Use of Lysine in Animal Feed, In Popular Culture

Other articles related to "lysine":

Lysine - In Popular Culture
... features dinosaurs that were genetically altered so that they could not produce lysine ... This was known as the "lysine contingency," and was supposed to prevent the cloned dinosaurs from surviving outside the park, forcing them to be dependent on lysine supplements ... Most vertebrates cannot produce lysine by default (it is an essential amino acid) ...
Lysine-pyruvate 6-transaminase
... In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction L-lysine + pyruvate L-2-aminoadipate 6-semi ... Other names in common use include lysine-pyruvate aminotransferase, and Lys-AT ...
Tryptophan Tryptophylquinone - See Also
... Polyglycylation Asparagine Deamidation Glycosylation Glutamine Transglutamination Lysine Methylation Acetylation Acylation Adenylylation Hydroxylation Ubiquitination Sumoylation ADP-ribosylation ...
SETD8
... corepressor activity • protein binding • protein-lysine N-methyltransferase activity • histone-lysine N-methyltransferase activity Cellular ...
L-lysine-lactamase
... In enzymology, a L-lysine-lactamase (EC 3.5.2.11) is an enzyme that catalyzes the chemical reaction L-lysine 1,6-lactam + H2O L-lysine Thus, the two ... The systematic name of this enzyme class is L-lysine-1,6-lactam lactamhydrolase ...