Lipothrixviridae - Virology


The viruses are enveloped and rod-shaped. The capsid varies considerably in length - 410-1950 nanometers (nm) - and is 24-38 nm in diameter. The envelope has a bilayer structure and include glycolipids and phospholipids, di-phytanyl tetraethers lipids. The phosphate residues of phospholipids are oriented towards the inside of the viron; the glycosyl residues of glycolipids are oriented towards the outside of the viron.

From either end of the viron are protrusions extending from the core through the envelope. The capsid itself is elongated and exhibits helical symmetry. The core itself is helical.

There two major capsid proteins (MCP1 and MCP2). The basic MCP1 protein forms a core around which the genomic dsDNA is wrapped, whereas MCP2 interacts with the genome with its basic N-terminal region and the hydrophilic C-terminal domain is embedded into the lipid envelope

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