Lipopolysaccharide N-acetylmannosaminouronosyltransferase

In enzymology, a lipopolysaccharide N-acetylmannosaminouronosyltransferase (EC 2.4.1.180) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-beta-D-mannosaminouronate + lipopolysaccharide UDP + N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide

Thus, the two substrates of this enzyme are UDP-N-acetyl-beta-D-mannosaminouronate and lipopolysaccharide, whereas its two products are UDP and N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase. Other names in common use include ManNAcA transferase, uridine, diphosphoacetylmannosaminuronate-, acetylglucosaminylpyrophosphorylundecaprenol, and acetylmannosaminuronosyltransferase.