Lipopolysaccharide

Lipopolysaccharide

Lipopolysaccharides (LPS), also known as lipoglycans, are large molecules consisting of a lipid and a polysaccharide joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria, act as endotoxins and elicit strong immune responses in animals.

Read more about Lipopolysaccharide:  Functions, Composition, LPS Modifications, Variability and Effect Upon Specificity, Immune Response

Other articles related to "lipopolysaccharide, lipopolysaccharides":

3-deoxyoctulosonase
... catalyzes the chemical reaction 3-deoxyoctulosonyl-lipopolysaccharide + H2O 3-deoxyoctulosonic acid + lipopolysaccharide Thus, the two substrates of ... The systematic name of this enzyme class is 3-deoxyoctulosonyl-lipopolysaccharide hydrolase ...
Lipopolysaccharide-binding Protein
... Lipopolysaccharide-binding protein is a protein that in humans is encoded by the LBP gene ... protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4 ... Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall ...
Lipopolysaccharide - Immune Response
... Bruce Beutler was awarded a portion of the 2011 Nobel Prize in Physiology or Medicine for his work demonstrating that TLR4 is the LPS receptor. ...
Lipopolysaccharide N-acetylmannosaminouronosyltransferase
... In enzymology, a lipopolysaccharide N-acetylmannosaminouronosyltransferase (EC 2.4.1.180) is an enzyme that catalyzes the chemical reaction UDP-N-acetyl-beta-D-man ...
Acyloxyacyl Hydrolase
3.1.1.77) is an enzyme that catalyzes the chemical reaction 3-(acyloxy)acyl group of bacterial lipopolysaccharide (lipid A moiety) 3-hydroxyacyl group of bacterial lipopolysaccharide + a fatty ... The enzyme removes from lipid A the secondary acyl chains that are needed for lipopolysaccharides to be recognized by the MD-2--TLR4 receptor on animal cells ... This reaction inactivates the lipopolysaccharide (endotoxin) ...