Lipid Raft

Lipid Raft

The plasma membrane of cells is made of a combination of glycosphingolipids and protein receptors organized in glycolipoprotein microdomains termed lipid rafts. These specialized membrane microdomains compartmentalize cellular processes by serving as organizing centers for the assembly of signaling molecules, influencing membrane fluidity and membrane protein trafficking, and regulating neurotransmission and receptor trafficking. Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer.

Read more about Lipid Raft:  Properties of Lipid Rafts, History, Common Types of Lipid Rafts, Lipid Raft and Signal Transduction, Visualization of Lipid Rafts, Controversy About Lipid Rafts

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Controversy About Lipid Rafts
... The role of rafts in cellular signaling, trafficking, and structure has yet to be determined despite many experiments involving several different methods, and their very existence is controversial ... Arguments against the existence of lipid rafts include the following First, a line tension should exist between the Lα and Lo phases ... Second, there is no consensus on lipid raft size, which has been reported anywhere between 1 and 1,000 nanometres ...