LHX2

LHX2

Identifiers Symbols LHX2; LH2; hLhx2 External IDs OMIM: 603759 MGI: 96785 HomoloGene: 55848 GeneCards: LHX2 Gene

Gene Ontology
Molecular function protein binding transcription factor activity
sequence-specific DNA binding transcription factor activity
zinc ion binding
sequence-specific DNA binding
metal ion binding
Cellular component nucleus
Biological process neural tube closure
transcription, DNA-dependent
axon guidance
mesoderm development
dorsal/ventral pattern formation
telencephalon regionalization
positive regulation of transcription, DNA-dependent
positive regulation of transcription from RNA polymerase II promoter
negative regulation of transcription regulatory region DNA binding
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9355 16870 Ensembl ENSG00000106689 ENSMUSG00000000247 UniProt P50458 Q9Z0S2 RefSeq (mRNA) NM_004789 NM_010710 RefSeq (protein) NP_004780 NP_034840 Location (UCSC) Chr 9:
126.76 – 126.8 Mb Chr 2:
38.34 – 38.37 Mb PubMed search

LIM/homeobox protein Lhx2 is a protein that in humans is encoded by the LHX2 gene.

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.

Read more about LHX2:  Interactions

Other articles related to "lhx2":

LHX2 - Interactions
... LHX2 has been shown to interact with CITED2. ...