Leucine 2,3-aminomutase

In enzymology, a leucine 2,3-aminomutase (EC is an enzyme that catalyzes the chemical reaction

(2S)-alpha-leucine (3R)-beta-leucine

Hence, this enzyme has one substrate, (2S)-alpha-leucine, and one product, (3R)-beta-leucine.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is (2S)-alpha-leucine 2,3-aminomutase. This enzyme participates in valine, leucine and isoleucine degradation. It employs one cofactor, cobamide.