Elizabeth Kaʻahumanu (c. 1768 – June 5, 1832) was queen regent of the Kingdom of Hawaiʻi and a wife of Kamehameha I. She was the king's favorite wife and also the most politically powerful, and continued to wield considerable power in the kingdom as the Kuhina Nui during the reigns of his first two successors.
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... Kaʻahumanu and King Kamehameha III negotiated the first treaty between the Kingdom of Hawaiʻi and the United States in 1826, under the administration ... In 1827, after Kaʻahumanu returned from a tour of the windward islands, her health steadily declined ...