Irreversible Inhibitors

Some articles on irreversible inhibitors, inhibitors, inhibitor, irreversible:

Enzyme Kinetics - Enzyme Inhibition and Activation - Irreversible Inhibitors
... Enzyme inhibitors can also irreversibly inactivate enzymes, usually by covalently modifying active site residues ... follow first order kinetics with respect to inhibitor ...
Enzyme Inhibitor - Irreversible Inhibitors - Examples of Irreversible Inhibitors
... (DFP) is shown as an example of an irreversible protease inhibitor in the figure above right ... Suicide inhibition is an unusual type of irreversible inhibition where the enzyme converts the inhibitor into a reactive form in its active site ... An example is the inhibitor of polyamine biosynthesis, α-difluoromethylornithine or DFMO, which is an analogue of the amino acid ornithine, and is used to treat African trypanosomiasis (sleeping sickness) ...