A technique called reverse genetics allows scientists to manipulate the genomes of influenza viruses and to transfer genes between viral strains. The technique allows the rapid generation of seed viruses for vaccine candidates that exactly match the anticipated epidemic strain. By removing or modifying certain virulence genes, reverse genetics also can be used to convert highly pathogenic influenza viruses into vaccine candidates that are safer for vaccine manufacturers to handle.
Other articles related to "reverse genetics, genetic, reverse genetic":
... While forward genetic screens are productive, a more straightforward approach is to simply determine the phenotype that results from mutating a given gene ... This is called reverse genetics ... Alternative methods of reverse genetic research include the random induction of DNA deletions and subsequent selection for deletions in a gene of interest, as well as the ...
... A molecular genetic approach is the creation of transgenic organisms that overexpress a normal gene of interest ...
Famous quotes containing the word reverse:
“We came home from the ridotto so late, or rather so early, that it was not possible for me to write. Indeed we did not go ... till past eleven oclock: but nobody does. A terrible reverse of the order of nature! We sleep with the sun, and wake with the moon.”
—Frances Burney (17521840)