Infant Respiratory Distress Syndrome

Infant respiratory distress syndrome (IRDS), also called neonatal respiratory distress syndrome or respiratory distress syndrome of newborn, previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of surfactant production and structural immaturity in the lungs. It can also result from a genetic problem with the production of surfactant associated proteins. IRDS affects about 1% of newborn infants and is the leading cause of death in preterm infants. The incidence decreases with advancing gestational age, from about 50% in babies born at 26–28 weeks, to about 25% at 30–31 weeks. The syndrome is more frequent in infants of diabetic mothers and in the second born of premature twins.

IRDS is distinct from pulmonary hypoplasia, another leading cause of neonatal death that involves respiratory distress.

Read more about Infant Respiratory Distress SyndromeClinical Course, Histopathology, Pathophysiology, Prevention, Treatment, Related Disorders, Famous Victims

Other articles related to "respiratory, infants":

Colin Morley - Publications
... Greenough A, Morley CJ, Hill CM Influence of respiratory function upon perinatal mortality and morbidity Lancet 1982 2(8291)211-212 Morley CJ, Hill CM ... apnoea a disorder resulting in episodes of severe arterial hypoxaemia in infants and young children Lancet 1985 2(8455)571-577 Greenough A, Pool J ...

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