IgA Nephropathy

IgA nephropathy (also known as IgA nephritis, IgAN, Berger's disease, Berger's syndrome and synpharyngitic glomerulonephritis) is a form of glomerulonephritis (inflammation of the glomeruli of the kidney). This should not be confused with Buerger's disease, an unrelated condition.

IgA nephropathy is the most common glomerulonephritis throughout the world Primary IgA nephropathy is characterized by deposition of the IgA antibody in the glomerulus. There are other diseases associated with glomerular IgA deposits, the most common being Henoch-Schönlein purpura (HSP), which is considered by many to be a systemic form of IgA nephropathy. HSP presents with a characteristic purpuric skin rash, arthritis, and abdominal pain and occurs more commonly in young adults (16-35 yrs old). HSP is associated with a more benign prognosis than IgA nephropathy. In IgA nephropathy there is a slow progression to chronic renal failure in 25-30% of cases during a period of 20 years.

Read more about IgA Nephropathy:  Signs and Symptoms, Diagnosis, Morphology, Pathophysiology, Natural History, Therapy, Genetics, Prognosis, Epidemiology, History

Other articles related to "iga nephropathy, iga":

IgA Nephropathy - History
... Hinglais, in 1968, were the first to describe IgA deposition in this form of glomerulonephritis (hence, Berger’s disease) ...
Henoch–Schönlein Purpura - Pathophysiology
... vasculitis in which complexes of immunoglobulin A (IgA) and complement component 3 (C3) are deposited on arterioles, capillaries, and venules ... As with IgA nephropathy, serum levels of IgA are high in HSP and there are identical findings on renal biopsy however, IgA nephropathy has a predilection for young adults while HSP is more predominant among ... Further, IgA nephropathy typically only affects the kidneys while HSP is a systemic disease ...