Hydrogenolysis

Hydrogenolysis is a chemical reaction whereby a carbon–carbon or carbon–heteroatom single bond is cleaved or undergoes "lysis" by hydrogen. The heteroatom may vary, but it usually is oxygen, nitrogen, or sulfur. A related reaction is hydrogenation, where hydrogen is added to the molecule, without cleaving bonds. Usually hydrogenolysis is conducted catalytically using hydrogen gas.

Read more about HydrogenolysisHistory, In The Petrochemical Industry, In The Laboratory

Other articles related to "hydrogenolysis":

Thioether - Reactions - Hydrogenolysis
... Thioethers undergo hydrogenolysis in the presence of certain metals R-S-R' + 2 H2 → RH + R'H + H2S Raney nickel is useful for stoichiometric reactions in organic synthesis whereas molybdenum-based catalysts ...
Hydrogenolysis - In The Laboratory
... In the laboratory, hydrogenolysis is used in organic synthesis ... ethers ROCH2C6H5 + H2 → ROH + CH3C6H5 Thioketals undergo hydrogenolysis using Raney nickel in the Mozingo reduction ... Laboratory hydrogenolysis is operationally similar to hydrogenation, and may be accomplished at atmospheric pressure by stirring the reaction mixture under a slight positive pressure of hydrogen gas ...
Adams' Catalyst - Uses
... It has shown to be valuable for hydrogenation and hydrogenolysis, dehydrogenation, and oxidation reactions ... to amines, platinum catalysts are preferred over palladium catalysts to minimize hydrogenolysis ... The catalyst is also used for the hydrogenolysis of phenyl phosphate esters, a reaction that does not occur with palladium catalysts ...
Hydrodesulfurization - Process Chemistry
... Hydrogenolysis is a type of hydrogenation and results in the cleavage of the C-X chemical bond, where C is a carbon atom and X is a sulfur (S), nitrogen (N) or oxygen (O ... The net result of a hydrogenolysis reaction is the formation of C-H and H-X chemical bonds ... Thus, hydrodesulfurization is a hydrogenolysis reaction ...
Common Protecting Groups - Amine Protecting Groups
... Protection of amines Carbobenzyloxy (Cbz) group - Removed by hydrogenolysis p-Methoxybenzyl carbonyl (Moz or MeOZ) group - Removed by hydrogenolysis, more labile than Cbz ... Benzyl (Bn) group - Removed by hydrogenolysis Carbamate group - Removed by acid and mild heating ... p-Methoxybenzyl (PMB) - Removed by hydrogenolysis, more labile than Benzyl 3,4-Dimethoxybenzyl (DMPM) - Removed by hydrogenolysis, more labile than p-me ...