Humanized

Some articles on humanized:

Humanized Antibody - Humanizing Via A Chimeric Intermediate
... Thereafter the chimera might be further humanized by the selective alteration of the sequence of amino acids in the Fab portion of the molecule ... Naming of humanized chimeras includes the stem for both designations (-xi- + -zu-) ... Otelixizumab is an example of a humanized chimera currently in clinical trials for treatment of rheumatoid arthritis and diabetes mellitus ...
Humanized Mouse
... A “humanized mouse” is a mouse carrying functioning human genes, cells, tissues, and/or organs ... Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics ...
Monoclonal Antibody Therapy - FDA Approved Therapeutic Antibodies
... Several auto-immune disorders Alemtuzumab Campath Genzyme 2001 humanized CD52 Chronic lymphocytic leukemia Basiliximab Simulect Novartis 1998 chimeric IL-2Rα receptor (CD25) Transplant ... Natalizumab Tysabri Biogen Idec/Élan 2006 humanized alpha-4 (α4) integrin, Multiple sclerosis and Crohn's disease Ofatumumab Arzerra 2009 Human CD20 Chronic lymphocytic leukemia ...
José Carioca - Comic Books
... in his own Brazilian comic books, in which he is portrayed as living with his friends Nestor (a humanized vulture) and Pedro (Portuguese Pedrão, a humanized dog), along with other characters his nephews ...
List Of Monoclonal Antibodies
... and breast cancer Afelimomab F(ab')2 mouse TNF-α sepsis Afutuzumab mab humanized CD20 lymphoma Alacizumab pegol F(ab')2 humanized VEGFR2 cancer ALD518 ? humanized IL-6 ... Benralizumab mab humanized CD125 asthma Bertilimumab mab human CCL11 (eotaxin-1) severe allergic disorders Besilesomab Scintimun mab mouse CEA-related antigen ... Cantuzumab ravtansine mab humanized MUC1 cancers Caplacizumab mab humanized VWF ? Capromab pendetide Prostascint mab mouse prostatic carcinoma cells prostate cancer (detection) Carlumab mab human CNTO888 ...