Hscs

Some articles on hscs, hsc:

MECOM - Association With Cancer - Oncogenesis and Induced Proliferation of HSCs
... been shown to have defects in both the development and proliferation of hematopoietic stem cells (HSCs) ... this is due to direct interaction with the trancription factor GATA-2, which is crucial for HSC development ... many times in vitro that EVI1 upregulation can induce proliferation and differentiation of HSCs and some other cell types such as rat fibroblasts ...
CD90 - Use in Stem Cell Biology
... hematopoietic stem cells or HSCs) ... During sorting, mouse HSCs fall under Thy1hi subpopulation, while human HSCs fall under the Thy1lo subpopulation ... In humans, Thy-1 is expressed on neurons and HSCs among others ...
Stem Cell Factor - Role in Hematopoiesis
... SCF plays a role in the regulation of HSCs in the stem cell niche in the bone marrow ... SCF has been shown to increase the survival of HSCs in vitro and contributes to the self renewal and maintenance of HSCs in-vivo ... HSCs at all stages of development express the same levels of the receptor for SCF (c-Kit) ...
PHSC - Functional Characteristics - Multipotency and Self-renewal
... As stem cells, HSC are defined by their ability to replenish all blood cell types (Multipotency) and their ability to self-renew ... It is known that a small number of HSCs can expand to generate a very large number of daughter HSCs ... transplantation, when a small number of HSCs reconstitute the hematopoietic system ...