Hexamethonium - Pharmacology

Pharmacology

It can act on receptors at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems, which are both regulated by nicotinic ligand-gated ionotropic acetylcholine receptors. Postganglionic sympathetic systems are usually regulated by norepinephrine (noradrenaline) (adrenergic receptors), whereas parasympathetic systems are acetylcholine-based, and instead rely on muscarinic receptors (some post-ganglionic sympathetic neurons, such as those stimulating sweat glands, release acetylcholine).

The organ system and adverse effects of ganglion blockers are due to the parasympathetic and sympathetic stimuli blockage at preganglionic sites. Side-effects include combined sympatholytic (e.g., orthostatic hypotension and sexual dysfunction) and parasympatholytic (e.g., constipation, urinary retention, glaucoma, blurry vision, decreased lacrimal gland secretion, dry mouth (xerostomia)) effects.

Read more about this topic:  Hexamethonium

Other articles related to "pharmacology":

Pharmacology - Education
... The study of pharmacology is offered in many universities worldwide in programs that differ from pharmacy programs ... Students of pharmacology are trained as biomedical researchers, studying the effects of substances in order to better understand the mechanisms which ... In addition, students of pharmacology must have detailed working knowledge of those areas in which biological or chemical therapeutics play a role ...
Pharmacoepidemiology
... To accomplish this study, pharmacoepidemiology borrows from both pharmacology and epidemiology ... Thus, pharmacoepidemiology is the bridge between both pharmacology and epidemiology ... Pharmacology is the study of the effect of drugs and clinical pharmacology is the study of effect of drugs on clinical humans ...
British Journal Of Clinical Pharmacology
... The British Journal of Clinical Pharmacology is a peer-reviewed medical journal published on behalf of the British Pharmacological Society by Wiley-Blackwell ... the British Pharmacological Society by Wiley-Blackwell is the British Journal of Pharmacology. 3.578, ranking it 53rd out of 260 journals in the category Pharmacology Pharmacy ...