Heptamer

Some articles on heptamer:

Anthrax Toxin - Extracellular Toxin Structure-function Relationship
... Petosa et al.solved the structure of a PA63 heptamer at 4.5 Å (0.45 nm) ... of a non-membrane bound pre-pore, the conformation of the heptamer before the complex extends a β-barrel through the plasma membrane to shuttle the LF and EF into the cytosol ... The heptamer formation causes no major changes in the conformation of each individual monomer, but by coming together, more than 15400 Ų (154 nm²) of protein surface is buried ...
Anthrax Toxin - Structure-function Relationship From Vesicle To Cytosol - Pore Formation
... Insertion of the PA Greek key motifs into the membrane occurs when the heptamer is acidified ... PA is endocytosed as a soluble heptamer attached to its receptors, with LF or EF attached to the heptamer as cargo ... in pH causes a disordered loop and a Greek-key motif in the PA domain 2 to fold out of the heptamer pre-pore and insert through the wall of the acidic vesicle, leading to pore ...
Hemolysin - Structure
... within the mushroom-shaped homo-oligomeric heptamer is a solvent-filled channel, 100 Å in length, that runs along the sevenfold axis and ranges from 14 Å to 46 Å in diameter ... The structure of the detergent-solubilized heptamer has been determined by X-ray crystallography to 1.9 Å resolution ... The heptamer has a mushroom-like shape and measures up to 100 Å in diameter and 100 Å in height ...