Glycosylases

Some articles on glycosylases, glycosylase:

Proteins Involved in Base Excision Repair - DNA Glycosylases
... DNA glycosylases are responsible for initial recognition of the lesion ... There are two categories of glycosylases monofunctional and bifunctional ... Monofunctional glycosylases have only glycosylase activity, whereas bifunctional glycosylases also possess AP lyase activity ...
DNA Glycosylase - Types of Glycosylases
... Crystal structures of many glycosylases have been solved ... Based on structural similarity, glycosylases are grouped into four superfamilies ... The UDG and AAG families contain small, compact glycosylases, whereas the MutM/Fpg and HhH-GPD families comprise larger enzymes with multiple domains ...
Types of Glycosylases - Uracil DNA Glycosylases
... In molecular biology, the protein family, Uracil-DNA glycosylase (UDG) is an enzyme that reverts mutations in DNA ... This entry represents various uracil-DNA glycosylases and related DNA glycosylases (EC), such as uracil-DNA glycosylase, thermophilic uracil-DNA glycosylase, GT/U mismatch-specific DNA ... Uracil DNA glycosylases remove uracil from DNA, which can arise either by spontaneous deamination of cytosine or by the misincorporation of dU opposite dA during DNA replication ...
Uracil-DNA Glycosylase
... Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA ... The first uracil DNA-glycosylase was isolated from Escherichia coli ... The human gene encodes one of several uracil-DNA glycosylases ...
DNA Glycosylase - Family - Glycosylases of Oxidized Bases
... A variety of glycosylases have evolved to recognize oxidized bases, which are commonly formed by reactive oxygen species generated during cellular metabolism ... lesion is initiated by the bifunctional DNA glycosylase OGG1, which recognizes 8-oxoG paired with C ... hOGG1 is a bifunctional glycosylase that belongs to the helix-hairpin-helix (HhH) family ...