Galactosyltransferase

Galactosyltransferase is a type of glycosyltransferase which catalyzes the transfer of galactose. An example is B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase.

The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates (EC 2.4.1.-) and related proteins into distinct sequence based families has been described. This classification is available on the CAZy (Carbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.

Glycosyltransferase family 31 (CAZY GH_31) comprises enzymes with a number of known activities; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.149); beta-1,3-galactosyltransferase (EC 2.4.1); fucose-specific beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1); globotriosylceramide beta-1,3-GalNAc transferase (EC 2.4.1.79).

Read more about Galactosyltransferase:  Human Galactosyltransferases

Other articles related to "galactosyltransferase":

Sucrose 6F-alpha-galactosyltransferase
... In enzymology, a sucrose 6F-alpha-galactosyltransferase (EC 2.4.1.167) is an enzyme that catalyzes the chemical reaction UDP-galactose + sucrose UDP + 6F-alpha-D-galactosyls ... The systematic name of this enzyme class is UDP-galactosesucrose 6F-alpha-D-galactosyltransferase ... uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase, UDPgalactosesucrose 6fru-alpha-galactosyltransferase, and sucrose 6F-alpha-galactotransferase ...
Lipopolysaccharide 3-alpha-galactosyltransferase
... In enzymology, a lipopolysaccharide 3-alpha-galactosyltransferase (EC 2.4.1.44) is an enzyme that catalyzes the chemical reaction UDP-galactose + lipopolysaccharide UDP + 3-alpha-D-gal ... this enzyme class is UDP-galactoselipopolysaccharide 3-alpha-D-galactosyltransferase ... UDP-galactoselipopolysaccharide alpha,3-galactosyltransferase, UDP-galactosepolysaccharide galactosyltransferase, uridine diphosphate ...
B4GALT7
... Beta-1,4-galactosyltransferase 7 also known as galactosyltransferase I is an enzyme that in humans is encoded by the B4GALT7 gene ... Galactosyltransferase I catalyzes the synthesis of the glycosaminoglycan-protein linkage in proteoglycans ...
Sphingosine Beta-galactosyltransferase
... In enzymology, a sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction UDP-galactose + sphingosine UDP ... of this enzyme class is UDP-galactosesphingosine 1-beta-galactosyltransferase ... names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactosesphingosine O-galac ...
Human Galactosyltransferases
... B4GALNT1 B4GALNT2 B4GALNT3 B4GALNT4 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GALT7. ...