Fibroblast Growth Factor Receptor 1 - Function


The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

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Other articles related to "function":

Integral - Fundamental Theorem of Calculus
... differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original function is retrieved ... to compute integrals by using an antiderivative of the function to be integrated ...
Integral - Extensions - Multiple Integration
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance ... Just as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the double integral of a positive function of two ... be obtained via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between the surface and ...
... Given a function f of a real variable x and an interval of the real line, the definite integral is defined informally to be the area of the region in the xy-plane bounded by the graph of f, the x ... may also refer to the notion of the antiderivative, a function F whose derivative is the given function f ... is connected with differentiation if f is a continuous real-valued function defined on a closed interval, then, once an antiderivative F of f is known, the definite integral ...
Currying - Motivation
... Currying is similar to the process of calculating a function of multiple variables for some given values on paper ... For example, given the function f(x,y) = y / x To evaluate f(2,3), first replace x with 2 ... Since the result is a function of y, this function g(y) can be defined as g(y) = f(2,y) = y/2 ...
Mitochondrion - Function
... The most prominent roles of mitochondria are to produce the energy currency of the cell, ATP (i.e ... phosphorylation of ADP), through respiration, and to regulate cellular metabolism ...

Famous quotes containing the word function:

    If the children and youth of a nation are afforded opportunity to develop their capacities to the fullest, if they are given the knowledge to understand the world and the wisdom to change it, then the prospects for the future are bright. In contrast, a society which neglects its children, however well it may function in other respects, risks eventual disorganization and demise.
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