**Function**

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

Read more about this topic: Fibroblast Growth Factor Receptor 1

### Other articles related to "function":

... differentiation and integration are inverse operations if a continuous

**function**is first integrated and then differentiated, the original

**function**is retrieved ... to compute integrals by using an antiderivative of the

**function**to be integrated ...

... In general, an integral over a set E of a

**function**f is written Here x need not be a real number, but can be another suitable quantity, for instance ... Just as the definite integral of a positive

**function**of one variable represents the area of the region between the graph of the

**function**and the x-axis, the double integral of a positive

**function**of two ... be obtained via the triple integral — the integral of a

**function**in three variables — of the constant

**function**f(x, y, z) = 1 over the above mentioned region between the surface and ...

... Given a

**function**f of a real variable x and an interval of the real line, the definite integral is defined informally to be the area of the region in the xy-plane bounded by the graph of f, the x ... may also refer to the notion of the antiderivative, a

**function**F whose derivative is the given

**function**f ... is connected with differentiation if f is a continuous real-valued

**function**defined on a closed interval, then, once an antiderivative F of f is known, the definite integral ...

... Currying is similar to the process of calculating a

**function**of multiple variables for some given values on paper ... For example, given the

**function**f(x,y) = y / x To evaluate f(2,3), first replace x with 2 ... Since the result is a

**function**of y, this

**function**g(y) can be defined as g(y) = f(2,y) = y/2 ...

**Function**

... The most prominent roles of mitochondria are to produce the energy currency of the cell, ATP (i.e ... phosphorylation of ADP), through respiration, and to regulate cellular metabolism ...

### Famous quotes containing the word function:

“If the children and youth of a nation are afforded opportunity to develop their capacities to the fullest, if they are given the knowledge to understand the world and the wisdom to change it, then the prospects for the future are bright. In contrast, a society which neglects its children, however well it may *function* in other respects, risks eventual disorganization and demise.”

—Urie Bronfenbrenner (b. 1917)

“The information links are like nerves that pervade and help to animate the human organism. The sensors and monitors are analogous to the human senses that put us in touch with the world. Data bases correspond to memory; the information processors perform the *function* of human reasoning and comprehension. Once the postmodern infrastructure is reasonably integrated, it will greatly exceed human intelligence in reach, acuity, capacity, and precision.”

—Albert Borgman, U.S. educator, author. Crossing the Postmodern Divide, ch. 4, University of Chicago Press (1992)

“No one, however powerful and successful, can *function* as an adult if his parents are not satisfied with him.”

—Frank Pittman (20th century)