Exanthema Subitum

Exanthema subitum (meaning sudden rash), also referred to as roseola infantum (or rose rash of infants), sixth disease (as the sixth rash-causing childhood disease), and (confusingly) baby measles, or three-day fever, is a disease of children, generally under two years old, although it has been known to occur in eighteen year olds, whose manifestations are usually limited to a transient rash ("exanthem") that occurs following a fever of about three day's duration.

It is frequently called roseola, although this term could be applied to any rose-colored rash.

It is caused by two human herpesviruses, HHV-6 (Human herpesvirus 6) and HHV-7, which are sometimes referred to collectively as Roseolovirus. There are two variants of HHV-6 (HHV-6a and HHV-6b) and studies in the US, Europe, Dubai and Japan have shown that exanthema subitum is caused by HHV-6b. This form of HHV-6 infects over 90% of infants by age 2. Research has shown that babies can be congenitally infected with HHV-6 via vertical transmission. This has been shown to occur in 1% of births in the United States.

Read more about Exanthema SubitumClinical Features, Vaccines and Treatment, Local Terms

Other articles related to "exanthema subitum":

Exanthema Subitum - Vaccines and Treatment
... There is no specific vaccine against or treatment for exanthema subitum, and most children with the disease are not seriously ill ... Exanthema subitum occurs in approximately 30% of children during primary HHV-6 infection ... Although they may be unnecessary for exanthema subitum, the usage of Cytomegalovirus treatments (valganciclovir, ganciclovir, cidofovir, and foscarnet) have shown some success ...