EGFR

EGFR is a four letter abbreviation that may refer to:

  • Epidermal growth factor receptor (EGFR)
  • Estimated glomerular filtration rate (eGFR)

Other articles related to "egfr":

Afatinib - Mechanism of Action
... and epidermal growth factor receptor (EGFR) kinases ... Afatinib is not only active against EGFR mutations targeted by first generation TKIs like erlotinib or gefitinib, but also against those not sensitive to these standard therapies ... Her2, it is investigated for breast cancer as well as other EGFR and Her2 driven cancers ...
Somatic Evolution In Cancer - Somatic Evolution in Therapeutic Resistance - Resistance To EGFR Targeting Drugs
... are epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors used for non-small cell lung cancer patients whose tumors have somatic mutations in EGFR ... patients who have developed clinical resistance to Gefitinib or Erlotinib point mutations in the EGFR gene targeted by the drugs, and amplification of MET, another receptor ... are currently assessing irreversible EGFR inhibitors (which inihibit growth even in cell lines with mutations in EGFR), the combination of EGFR and MET kinase inhibitors, and Hsp90 inihibitors (EGFR and ...
Transheterozygote
... in the Epidermal growth factor receptor (Egfr), a gene required for communication between cells, can be dominantly enhanced by a recessive mutation in Notch ... A transheterozygote between Egfr and Notch has the genotype Notch/+ Egfr/+ (where Notch and Egfr represent mutant alleles, and + represents wildtype alleles) ... The dominant interaction between Egfr and Notch suggested that the Egfr and Notch signalling pathways act together within the cell to affect the pattern of veins in the fly's wings ...
Lapatinib - Mode of Action - Biochemistry
... Lapatinib inhibits the tyrosine kinase activity associated with two oncogenes, EGFR (epidermal growth factor receptor) and HER2/neu (Human EGFR type 2) ...