Some articles on dna, dna damage:
Wee1 - Role in Cancer
... The mitosis promoting factor MPF also regulates DNA-damage induced apoptosis ... by WEE1 causes aberrant mitosis and thus resistance to DNA-damage induced apoptosis ... factor 2 (KLF2) negatively regulates human WEE1, thus increasing sensitivity to DNA-damage induced apoptosis in cancer cells ...
... The mitosis promoting factor MPF also regulates DNA-damage induced apoptosis ... by WEE1 causes aberrant mitosis and thus resistance to DNA-damage induced apoptosis ... factor 2 (KLF2) negatively regulates human WEE1, thus increasing sensitivity to DNA-damage induced apoptosis in cancer cells ...
Cyclin D - Regulation - Regulation in Humans
... There are two ways in which DNA damage affects Cdks ... Following DNA damage, cyclin D (cyclin D1) is rapidly and transiently degraded by the proteasome ... Another way in which DNA damage targets Cdks is p53-dependent induction of p21, which inhibits cyclin E-Cdk2 complex ...
... There are two ways in which DNA damage affects Cdks ... Following DNA damage, cyclin D (cyclin D1) is rapidly and transiently degraded by the proteasome ... Another way in which DNA damage targets Cdks is p53-dependent induction of p21, which inhibits cyclin E-Cdk2 complex ...
Transcription-coupled Repair - Nucleotide Excision Repair in Eukaryotes - Dual Incision
... TFIIH and XPG are first recruited to the site of DNA damage (XPG stabilizes TFIIH) ... subunits of XPD and XPB act as a helicase and ATPase respectively - they help unwind DNA and generate a junction between the double-stranded and single-stran ... In addition to stabilizing TFIIH, XPG also has endonuclease activity it cuts DNA damage on the 3' side while the XPF-ERCC1 heterodimeric protein cuts on the 5' side ...
... TFIIH and XPG are first recruited to the site of DNA damage (XPG stabilizes TFIIH) ... subunits of XPD and XPB act as a helicase and ATPase respectively - they help unwind DNA and generate a junction between the double-stranded and single-stran ... In addition to stabilizing TFIIH, XPG also has endonuclease activity it cuts DNA damage on the 3' side while the XPF-ERCC1 heterodimeric protein cuts on the 5' side ...
Pancratistatin - Biological Activity
... Pancratistatin does not cause DNA double-strand breaks or DNA damage prior to the execution phase of apoptosis in cancer cells ... treatment, indicated that VP-16 causes substantial DNA damage in normal non-cancerous blood cells, while Pancratistatin does not cause any DNA double-strand breaks or DNA damage in non-ca ... Since Pancratistatin shows little structural similarity to any DNA intercalating drug or to paclitaxel derivatives, it appears to be non-genotoxic ...
... Pancratistatin does not cause DNA double-strand breaks or DNA damage prior to the execution phase of apoptosis in cancer cells ... treatment, indicated that VP-16 causes substantial DNA damage in normal non-cancerous blood cells, while Pancratistatin does not cause any DNA double-strand breaks or DNA damage in non-ca ... Since Pancratistatin shows little structural similarity to any DNA intercalating drug or to paclitaxel derivatives, it appears to be non-genotoxic ...
CHEK1
... cytosol Biological process • cell cycle checkpoint • DNA damage checkpoint • G2/M transition of mitotic cell cycle • DNA replication • DNA repair ...
... cytosol Biological process • cell cycle checkpoint • DNA damage checkpoint • G2/M transition of mitotic cell cycle • DNA replication • DNA repair ...
Famous quotes containing the words damage and/or dna:
“I came to explore the wreck.
The words are purposes.
The words are maps.
I came to see the damage that was done
and the treasures that prevail.”
—Adrienne Rich (b. 1929)
“Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.”
—William Gibson (b. 1948)
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